Publications

H. Kong, N. Kahatapitiya, K. Kingsley, W. L. Salo, P. M. Anderson, Y. Wang and P. J. Walsh “Induction of Carbamoyl-phosphate Synthetase III and Glutamine Synthetase mRNA during Confinement Stress in Gulf Toadfishand (Opsanus beta)”, the Journal of Experimental Biology 2000, 203, 311-320.

H. Kong, D. D. Edberg, P. J. Walsh, W. L. Salo, J. Korte, and P. M. Anderson, “Nitrogen Excretion and Expression of Carbamoyl-Phosphate Synthetase III Activity and mRNA in Extrahepatic Tissues of Largemouth Bass (Micropterus salmoides)”, Arch. Biochem. Biophys., 1998 Feb 15; 350(2):157- 168.

H. Kong, K. Zhao, “Effect of Astragalan on Secretion of Tumor Necrosis Factors in Human Peripheral Blood Mononuclear Cells”, Chinese Journal of Integrated Traditional and Western Medicine 1993; 13(5): 263-265.

H. Kong, K. Zhao, “Enhancement of the Th Cell Activity in Old Mice by Astragalan”, FASEB Journal, 1992, V6, N4(Feb 26), PA1394.

K. Zhao, H. Kong, D. Su, “ Enhancement of IL-2 Production of Spleen Cells and IL-2 Activity in Aged Mice by Astragalan Administration”, Journal of Fujian medical school, 1992, 26(3), 199-203.

K. Zhao, D. Su, X. Zhang, H. Kong, “Application of Affinity Absorbing Endotoxin-gel in Pharmaceutical Industry”, Chinese Journal of Pharmaceuticals, 1993, 24(2).

Chun C, et al. “Characterization of production bioreactors and media preparation tanks for process development and manufacturing, Cell Culture Engineering XIV Poster Session, 2014

Chung Chun, Katy Heineken, Dongmei Szeto, Thomas Ryll, Steve Chamow, and John D. Chung “Application of Factorial Design to Accelerate Identification of CHO Growth Factor Requirements”. Biotechnol. Prog. 2003 19, 52-57

Chun C, et al. Application of Factorial Design to Accelerate Identification of CHO Growth Factor Requirements, Cell Culture Engineering VIII Poster Session, 2002

Murphy TJ, Pavlath GK, Wang X, Boss V, Abbott KL, Robida AM, Nichols J, Xu K, Ellington ML, Loss JR 2nd. (2002) Retroviral vectors applied to gene regulation studies. Methods Enzymol. 345: 539-51.

Wang X, Ono K, Kim SO, Kravchenko V, Lin SC, Han J. (2001) “Metaxin is required for tumor necrosis factor-induced cell death”. EMBO Rep. 2(7): 628-33.

Wang X, Han J. (2000) “Elucidating tumor necrosis factor signaling pathway using a functional gene identification approach”. Immunol Res. 21(2-3): 55-61.

Wang X, McGowan CH, Zhao M, He L, Downey JS, Fearns C, Wang Y, Huang S, Han J. (2000) “Involvement of the MKK6-p38gamma cascade in gamma- radiation-induced cell cycle arrest”. Mol Cell Biol. 20(13): 4543-52.

Wang X, Murphy TJ. (2000) “The inducible cAMP early repressor ICERII-g inhibits CREB and AP-1 transcription but not AT1 receptor gene expression in vascular smooth muscle cells”. Mol Cell Biochem. 212(1-2): 111-9.

Wang X, Murphy TJ. (1998) “Inhibition of cyclic AMP-dependent kinase by expression of a protein kinase inhibitor/enhanced green fluorescent fusion protein attenuates angiotensin II-induced type 1 AT1 receptor mRNA down- regulation in vascular smooth muscle cells”. Mol Pharmacol. 54(3): 514-24.

Wang X, Nickenig G, Murphy TJ. (1997) “The vascular smooth muscle type I angiotensin II receptor mRNA is destabilized by cyclic AMP-elevating agents”. Mol Pharmacol. 52(5): 781-7.

Wang, X.-F. , and Zhu, P.-H. (1994). “Effect of activation of protein kinase C on excitation-contraction coupling in frog twitch muscle fibres”. Pflugers Arch. 428: 224-231.

Wang X, Sohr S, Cataniag F, et al. (2004) “Optimization of AAV vector production by transient Transfection”. Poster presentation at 7th Annual Meeting of the American Society of Gene Therapy 2004.

Qu G, Wang X, Luna JM, et al. (2004) “Development of a scalable column chromatography-based purification process to manufacture empty capsid-free AAV vectors”. Poster presentation of Gene Therapy 2004.

Qu G, Sperinde GV, Wang X, et al. (2002) “Characterization of AAV vectors expressing human coagulation factor IX produced at intermediate scale”. Poster presentation at 5th Annual Meeting of the American Society of Gene Therapy 2002.

Wang X, Cunningham J, Zhu Z, et al. (2001) “Effect of empty capsids of type 2 adeno-associated virus on transgene expression both in vitro and in vivo”. Poster presentation at 4th Annual Meeting of the American Society of Gene Therapy 2001.

Michael Zamloot, Wendy Chao, Ling-Ling Kang, Julie Ross, Roger Fu, “Remoxy®: A Novel Formulation of Extended-Release Oxycodone Developed by Using the ORADUR® Technology”, The Journal of Applied Research, 10 (3), pp. 88, 2010

H. Dehnad, S. Berry, P Fereira, R. Ayer, A Obrien, G. Chen, D. Priebe, J. Matuura, A. Muchnik, L.L. Kang, A. Chester, J.C. Wright. “Functionality of Osmotically Driven Implantable Therapeutic Systems (DUROS Implants): Effect of Osmotic Pressure and Delivery of Suspension Formulation of Peptides and Protein”, poster at the Controlled Release Society Annual Meeting, 2000

Andrew Guzzetta, Ling-Ling Kang, Hoai-Thu Truong, Patricia Baldwin. “Conversion of a Standard HPLC into an Automated Capillary HPLC with LC/MS Applications”, poster at the ASMS Conference, 1996

Z. Shahrokh, Irina Belin, Gert Eberlein, Mark Busch, Ling-Ling Kang, Amy Wong, Cheryl Anderson, Diane Blumenthal and Y. John Wang. “Cellulose- Cleaving Activity Containing E.Coli-Produced Recombinant Protein”, Bio Pharm. March 1995, 8 (2), pp. 32

Gorden Porter, Robert Scarborough, Yu Wang, Dale Schenk, Glenn McEnroe, Ling-Ling Kang, and John Lewicki. “Recombinant Expression of a Secreted Form of Atrial Natriuretic Peptide Clearance Receptor”, The Journal of Biological Chemistry, 264 (24), pp. 14179-14184, 1989

Robert Scarborough, Glenn McEnroe, Ann Arfsten, Ling-Ling Kang, Karen Schwartz, and John Lewicki, “D-Amino Acid-Substituted Atrial Natriuretic Peptide Analogs Reveal Novel Receptor Recognition Requirement”, The Journal of Biological Chemistry, 263 (32), pp. 16818-16822, 1988

J. Lewicki, D. Schenk, F. Fuller, G. Porter, G. McEnroe, A. Arfsten, K. Schwartz, L-L. Kang, T. Maack, and R. Scarborough “Pharmacological and Biological Studies of Atrial Nitriuretic Peptide Receptor Subpopulations”, in Advance in Atrial Peptide Research (Brenner, B. M. and Laragh, J. H., eds) Vol. II, pp. 31-39, Raven Press, New York, 1988

Robert Scarborough, Gelnn McEnroe, Ann Arfsten, Ling-Ling Kang, Karen Schwartz, and Gordon Porter, J. “Linear Fragment of ANP’s Bind to C-Receptors with High Affinity”, Cell Biochem., 111, pp. 20 (abstr.), 1988

Robert Scarborough, Dale Schenk, Glenn McEnroe, Ann Arfsten, Ling-Ling Kang, Karen Schwartz, and John Lewicki, “Truncated Atrial Natriuretic Peptide Analogs”, The Journal of Biological Chemistry, 260 (28), 12960-12964, 1986


Patents

Kong H., et al., Mediators of signal transduction. U.S. patent Docket number 69972/85916.

Kang L., et al., Implantable Device for Long-term Delivery of Drugs (US20110106006)

Kang L., et al., In-Situ Forming Porous Scaffold (US20070178159)

Kang L., et al., Polyoxaester Suspending Vehicles for Use with Implantable Delivery Systems (US20060246138)

Kang L. et al., Stabilized Solid-state Polypeptide Particles (WO2004039392)