Scarab Genomics and Bionova Enter Exclusive Licensing Partnership to Advance High-Efficiency Plasmid DNA Production

February 3, 2026, Madison, WI — Scarab Genomics, a biotechnology company specializing in the engineered Clean Genome® E. coli platform for reliable microbial production, today announced an exclusive licensing partnership with Bionova Scientific, a leading contract development and manufacturing organization (CDMO) supporting advanced biologics programs. Under the agreement, Bionova has obtained exclusive rights to utilize one of Scarab’s proprietary Clean Genome® strains for plasmid DNA (pDNA) production.

Scarab’s Clean Genome platform comprises a library of engineered E. coli strains designed to eliminate mobile genetic elements, minimize genomic instability, and reduce burdensome host functions-resulting in higher plasmid yields, improved lot-to-lot consistency, and streamlined downstream purification. The strain licensed to Bionova incorporates Scarab’s production-enhancing genetic modifications optimized specifically for pDNA manufacturing.

“We’re excited to formalize this partnership with Bionova,” said Venkat Balakrishnan, PhD, Director of Commercial Operations at Scarab Genomics. “Their commitment to supporting innovative therapeutics aligns well with Scarab’s mission to provide high-performance microbial platforms that accelerate development and manufacturing for next-generation biologics.”

The exclusive license enables Bionova to integrate the Clean Genome strain into its pDNA production workflows to support client programs across modalities, including mRNA, viral vectors, and emerging genetic medicine platforms.

“Reliable access to high-quality plasmid DNA is critical for many of the programs we support,” said Darren Head, President at Bionova Scientific. “Scarab’s Clean Genome technology strengthens our ability to deliver consistent, scalable, and regulatory-aligned pDNA manufacturing solutions to our customers.”

About Scarab Genomics

Scarab Genomics, LLC is a biotechnology company advancing stable microbial manufacturing through Clean Genome® E. coli strains and the C-Flow™ continuous fermentation system. The platform improves genomic stability and expression, supporting a wide range of applications from research through production.

About Bionova Scientific

Bionova Scientific www.bionovascientific.com, part of the Asahi Kasei Group, is a bespoke CDMO providing end-to-end development and GMP manufacturing for recombinant proteins and plasmid DNA. We support biotherapeutic programs at any stage, from cell line development through commercial-ready GMP production.

With protein operations in Fremont, California and a dedicated plasmid DNA facility in Houston, Texas, Bionova delivers specialized, high-quality solutions with speed and precision.

Founded in 2014 and acquired by Asahi Kasei in 2022, Bionova combines the agility and personalized service of a boutique CDMO with the global strength, resources, and quality standards of a multi-billion-dollar organization, making us a trusted partner from discovery to GMP.

Scarab Genomics Contact

Anne Stover, Director of Marketing and Business Development
Scarab Genomics
[email protected]

Bionova Contact
Cheryl Sturgis, Head of Marketing
[email protected]

About Bionova Scientific

Bionova Scientific, an Asahi Kasei company, a bespoke contract development and manufacturing organization (CDMO) with deep expertise in complex biologics manufacturing and p-DNA for cell and gene therapy applications. With facilities in Fremont, California, and The Woodlands, Texas, Bionova delivers scientifically rigorous, high-quality, and highly personalized solutions to support biotherapeutic innovators from early development through commercial readiness.

About Syenex

Syenex is an open-science genetic medicines platform company that enables developers to program cells with precision and scale. Leveraging synthetic biology and a global network of contract development and manufacturing organizations (CDMOs), Syenex provides plug-and-play delivery platforms, spanning discovery through GMP manufacturing, so genetic medicine developers can rapidly advance ideas to clinical impact. Founded in 2022, Syenex has assembled a portfolio of cell-specific ex vivo and in vivo delivery platforms and over 50 partnerships with industry leaders across biopharma and academia. Learn more at www.syenex.com.

For more information, please contact:

Bionova Scientific, LLC
Cheryl Sturgis
[email protected]

Syenex, Inc.
Teresa Nikolich
[email protected]

Share this article